Skin Sensitization Assessment of MariXBioHeal™ Collagen

Author: Rozhan Vista Mehr Ltd.  |  Category: Research

Overview

To evaluate the potential for skin sensitization, MariXBioHeal™ Native Marine Type I Collagen underwent the Guinea Pig Maximization Test (GPMT). The study was conducted at the National Institute of Genetic Engineering and Biotechnology (NIGEB) following ISO 10993-10 protocols.

Method

• Species: Albino guinea pigs
• Groups: 10 test animals, 5 controls
• Phases: Intradermal induction → topical induction → challenge
• Observation period: 24h and 48h post-challenge

Results

• Test animals: all scores = 0
• Control animals: all scores = 0
• No erythema or edema observed
• Outcome: Non-sensitizing

Key Message

MariXBioHeal™ collagen showed no evidence of allergic or sensitization reactions, confirming its compliance with ISO 10993-10.

Keywords: Skin sensitization, ISO 10993-10, GPMT, MariXBioHeal collagen, biocompatibility test