Research

What Are Biomaterials?

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Understanding Biomaterials and the Emerging Role of Marine-Derived Materials in Modern Biomedicine Author: Rozhan Vista Mehr Ltd.  |  Category: Research | Date Published: October 2025 Abstract Biomaterials represent one of the most transformative innovations in modern biomedicine, offering solutions that merge biology and engineering. This white paper explores the foundation, classification, and growing significance of marine-derived biomaterials as […]

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Skin Sensitization (ISO 10993-10, GPMT)

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Skin Sensitization Assessment of MariXBioHeal™ Collagen Author: Rozhan Vista Mehr Ltd.  |  Category: Research Overview To evaluate the potential for skin sensitization, MariXBioHeal™ Native Marine Type I Collagen underwent the Guinea Pig Maximization Test (GPMT). The study was conducted at the National Institute of Genetic Engineering and Biotechnology (NIGEB) following ISO 10993-10 protocols. Method Species: Albino guinea pigs

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Skin Irritation (ISO 10993-10, Rabbit Model)

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Skin Irritation Test of MariXBioHeal™ Collagen Author: Rozhan Vista Mehr Ltd.  |  Category: Research Overview MariXBioHeal™ Native Marine Type I Collagen was tested for dermal irritation potential using albino rabbits. The study was performed at the Iran National Institute of Genetic Engineering and Biotechnology (NIGEB) according to ISO 10993-10. Method Species: Albino rabbits (n=3) Exposure duration: 72 hours

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In-Vitro Cytotoxicity (ISO 10993-5, MTT Assay)

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In-Vitro Cytotoxicity Evaluation of MariXBioHeal™ Collagen Author: Rozhan Vista Mehr Ltd.  |  Category: Research Overview Rozhan Vista Mehr Co. performed an in-vitro cytotoxicity study on MariXBioHeal™ Native Marine Type I Collagen to confirm its biological safety. The evaluation was conducted at the National Institute of Genetic Engineering and Biotechnology (NIGEB) at the Iran Polymer and Petrochemical Institute  under

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Extracellular Matrix and the role of Native Collagen in Regenerative Medicine

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Extracellular Matrix and the Role of Native Collagen in Regenerative Medicine 1. Why the Extracellular Matrix Matters The extracellular matrix (ECM) is more than just a structural scaffold. It regulates how cells grow, migrate, and repair damaged tissue. Made of proteins, enzymes, and growth factors, the ECM provides the biological signals that guide regeneration. When

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The Role of Native Collagen in Regenerative Medicine Research: From Structure to Application

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The Role of Native Collagen in Regenerative Medicine Research From Structure to Application Author: Rozhan Vista Mehr Ltd.  |  Category: Research Introduction Regenerative medicine is a rapidly evolving field focused on restoring damaged tissues and organs by stimulating the body’s own healing processes. One of the foundational components in this scientific revolution is collagen—a primary

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What Is Native Collagen?

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What Is Native Collagen? Structure, Benefits, and Why It Matters Collagen is the most abundant protein in the human body and the primary structural component of connective tissues. While the term “collagen” is often used broadly, not all collagens are created equal. The distinction between native collagen and hydrolyzed collagen is critical — especially in

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Evaluate the Immune Properties of Marine-Based Collagen Dressing in Wound Care Management

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Evaluate the Immune Properties of Marine-Based Collagen Dressing in Wound Care Management A Pre-Clinical Evaluation of MariXBioHeal™ by Rozhan Vista Mehr Author: Rozhan Vista Mehr Ltd. | Lab: Nikopharmed Arya Co Laboratory Keywords: Collagen, Wound Healing, Fish Waste, Biomedical, Immune Properties Introduction In recent years, wound care products have attracted much research attention, aiming to

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